Abstract visualization of a porous synthetic bone graft lattice structure

Next-GenerationSynthetic Bone Graftfor Critical-Size Defects

GraftID combines calcium phosphate and magnesium phosphate biomaterials expertise with controlled resorption and regenerative microenvironment design. The goal: a better-balanced process between new bone formation and material resorption.

100% Synthetic
TÜBİTAK 1812 BiGG
Patent Application Filed

Technological Approach

GraftID designs a platform that supports the pace of new bone formation while preserving the material's functional presence. Controlled resorption, osteoconduction, and a regenerative microenvironment come together in a single product.

Controlled Resorption

Built on beta-tricalcium phosphate and K-struvite, the material is designed to maintain its functional presence at the defect site for a clinically meaningful period.

Osteoconductive Architecture

A porous scaffold that supports natural bone architecture, providing space for cell attachment and tissue integration during new bone formation.

Fully Synthetic Composition

Contains no animal- or human-derived material. The 100% synthetic composition offers supply and standardization advantages as an alternative to biologically sourced grafts.

Clinical Applications

The initial target market is orthopedic and dental applications in Türkiye. The product platform is designed to be adaptable to additional surgical disciplines over time.

Orthopedics

Trauma & Reconstruction

Osteoconductive scaffold support for high-energy trauma, revision surgery, tumor resection, and critical long-bone defects.

Dentistry

Implantology & Augmentation

Graft forms suitable for surgical use in implantology, periodontal, and maxillofacial bone augmentation.

Neurosurgery

Cranial & Spinal Surgery

An adaptable product platform open to development for suitable indications in cranial and spinal surgery.

Future potential:
Veterinary Orthopedics
Research Market

Why GraftID?

Balanced Timing

A design focused on balancing the timing between resorption and new bone formation, so the graft maintains its function long enough in critical defects.

Positioned for Critical-Size Defects

The product is specifically positioned for critical-size bone defects, where fast-resorbing synthetic grafts fall short.

Adaptable Product Platform

An injectable structure plus granule, paste, and other formats adaptable to different surgical indications — a multi-form product platform.

Cross-sectional microstructure visualization showing the synthetic graft material integrating with natural bone cells
Microstructure visualization

The porous osteoconductive scaffold provides space for tissue integration and vascularization.

R&D and Validation Status

Lab-scale formulation and in vitro validation studies have been carried out under the TÜBİTAK 1812 project, with positive findings on the targeted biological activity.

Formulation development

Completed / optimization ongoing

Completed
Physicochemical characterization

XRD, FTIR, morphology, particle size, swelling and degradation tests

Completed
In vitro biocompatibility

Cytotoxicity and cellular response studies

Completed
Osteogenic validation

Pre-osteoblast models and mineralization-focused analyses

Completed
Osteoclast response

RAW264.7 and RANKL-based resorption mechanism studies

Completed
Animal study

Small-animal bone defect model; studies at an advanced stage

In progress
Sterilization and shelf life

Gamma sterilization and packaging validation plan

Planned
Production scale-up

Pilot production and process standardization being planned

Planned

Note: GraftID is at the pre-seed / product validation and regulatory preparation stage.

Strategic partnerships

Let's develop together

Get in touch with our team for distribution, clinical collaboration, co-development, and investment discussions. We are building a medical technology platform extending from Türkiye to Europe.

  • Orthopedic and dental product distributors
  • Hospitals, clinics, and early-adopter centers
  • Medical device manufacturers and pilot production partners
  • Universities and research laboratories

GRAFTID Teknoloji ve Sanayi A.Ş.

Headquarters

Teknopark Istanbul — Cube Incubation

Founder

Asst. Prof. İlayda Duru Türkmen

Field of Activity

Medical technologies, biomaterials, and regenerative medicine

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